- Certificate
- IP-COA-IG-261005
- Issued
- 4 October 2026
- Status
- released
IGF-1 LR3
Recombinant long-acting analogue of insulin-like growth factor 1
- 0.1 mg
- 1 mg
- IdentityConfirmedMass spectrometry
- Endotoxin< 0.125 EU/mgKinetic chromogenic LAL
- SterilityNo growthMembrane filtration
- Analysed2 October 2026Batch made 1 October 2026
Full analytical results
Tests and specifications
| Test | Method | Specification | Result | Status |
|---|---|---|---|---|
| Appearance | Visual inspection | White lyophilised powder or cake | Conforms | Pass |
| Purity | SEC-HPLC, monomer, 280 nm | ≥ 99.0% | 99.54% | Pass |
| Identity | ESI-MS, intact mass | [M+9H]9+ = 1014.07 ± 0.50 | 1014.22 | Pass |
| Aggregate content | SEC-HPLC, high molecular weight species | ≤ 1.0% | 0.11% | Pass |
| Protein content | UV absorbance at 280 nm | ≥ 95.0% of label claim | 97.7% | Pass |
| Host cell protein | ELISA | ≤ 100 ppm | < 35 ppm | Pass |
| Residual host DNA | qPCR | ≤ 10 ng per vial | < 0.5 ng per vial | Pass |
| Residual moisture | Karl Fischer titration | ≤ 5.0% | 2.27% | Pass |
| Bacterial endotoxins | Kinetic chromogenic LAL | < 1.0 EU/mg | < 0.125 EU/mg | Pass |
| Sterility | Membrane filtration (USP <71>) | No growth | No growth | Pass |
| Elemental impurities | ICP-MS (USP <232> and <233>) | Pb ≤ 5, Cd ≤ 2, As ≤ 15, Hg ≤ 3 µg/day (ICH Q3D, parenteral) | Conforms | Pass |
Chromatogram
Size-exclusion trace for this batch. One dominant peak at 11.9 minutes, 99.54% of the total peak area, largest single impurity 0.11%.
Mass spectrum
Electrospray ionisation. Expected 1014.07, observed 1014.22, a difference of 0.15 m/z at charge state 9. The neighbouring peaks are the same molecule at the charge states either side of it.
Reference data
- Also known as
- Long R3 IGF-I, LR3-IGF-1
- CAS number
- 143045-27-6
- Molecular formula
- C400H625N111O115S9
- Molecular weight
- 9117.60 g/mol
- Modifications
- Eighty-three residues: insulin-like growth factor 1 with glutamate 3 replaced by arginine, and a thirteen-residue extension at the front. Three disulfide bonds. The formula and mass shown are for the reduced chain; the folded protein is six hydrogens lighter, at 9111.55 g/mol.
Public reference values for the compound, not measurements on this batch. The batch measurements are in the table above.
Storage and handling
- Unopened
- 2 to 8 °C, away from light
- Long term
- −20 °C, lyophilised, for the stated shelf life
- Reconstituted
- 2 to 8 °C, use within 2 weeks; do not freeze and thaw
- In transit
- Stable at ambient temperature for up to 14 days
- Reconstitute with
- Bacteriostatic water
The vial this covers
The label on your vial carries the same batch code as this certificate, IP-IG-261001, and the QR goes to the results for it. If the code on the vial is not this one, the certificate for it is on this page under earlier batches.
Sticker shown at its printed size, 40 by 20 mm. Cap colour may vary by batch.
Release
- Batch date
- 1 October 2026
- Analysis date
- 2 October 2026
- Issue date
- 4 October 2026
- Best before
- October 2028
- Released by
- Quality review, Indigo Peptides
- Document
- Valid only in its original, unmodified form
Results are taken from the batch testing documentation for this exact batch, supplied with the finished vials and held on file by us. Every value above is for the batch named on this certificate and for no other.
Holding an older vial?
| Batch | purity | Analysed |
|---|---|---|
| IP-IG-260914 | 99.49% | 15 September 2026 |
If the code on your vial is one of these, it is an earlier batch of ours and these are its results. A result we have published is never removed and never recalculated.